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Public Health 190 (Bradman)

Does the Dose Make the Poison? Introduction to Toxicology and Risk Assessment

Critical Appraisal Tools

From the Center for Evidence-Based Medicine (CEBM) from University of Oxford:

Critical appraisal is the systematic evaluation of clinical research papers in order to establish:

  1. Does this study address a clearly focused question?
  2. Did the study use valid methods to address this question?
  3. Are the valid results of this study important?
  4. Are these valid, important results applicable to my patient or population?

If the answer to any of these questions is “no”, you can save yourself the trouble of reading the rest of it.

Critical Appraisal Tools:

Defining Eligibility and Reducing Bias

Catalog of Bias (CEBM & Oxford University)

Office of Health Assessment and Translation (OHAT) Division of the National Toxicology Program